New equine respiratory condition described
In a paper to be published in the Veterinary Journal, Lotte Winther, a PhD student in the Department of Large Animal Sciences at the University of Copenhagen, and colleagues present data from seven horses with respiratory disease associated with S. maltophilia infection. The horses were treated at three equine referral hospitals in Denmark in 2007.
The report documents the clinical findings, laboratory diagnosis and response to treatment.
All cases had a history of chronic coughing. Endoscopic examination revealed copious mucopurulent exudate in the lower trachea. Culture of the tracheal exudate produced grey, slow-growing colonies, which were identified as S. maltophilia by both culture and DNA testing.
All isolates had a similar antibiotic susceptibility pattern. They were resistant to many antibiotics used to treat respiratory infections in horses, including all penicillins, cephalosporins, aminoglycosides and rifampicin.
"The results from susceptibility testing and clinical response to treatment suggest prolonged administration of tetracyclines (greater than 10 to 14 days) is an effective treatment, especially for adult horses," advise the researchers.
The findings suggest that S. maltophilia can act as a respiratory pathogen. The researchers advise that the organism be included in the differential diagnosis of horses with respiratory disease associated with copious mucopurulent exudate.
They stress that many antibiotics commonly used to treat equine respiratory infections are not effective against S. maltophilia.
For more details see:
Association of Stenotrophomonas maltophilia infection with lower airway disease in the horse: A retrospective case series.
Winther L, Andersen RM, Baptiste KE, Aalbæk B, Guardabassi L.
Vet J. 2009 Sep 14.
http://dx.doi.org/10.1016/j.tvjl.2009.08.026
Reproduced with kind permission of Mark Andrews BVM&S CertEP MRCVS
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Added on: 23/04/10.
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